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KMID : 0388220070140040363
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Journal of the Korean Rheumatism Association
2007 Volume.14 No. 4 p.363 ~ p.368
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Overlap Syndrome of Amyopathic Antisynthetase Syndrome and Systemic Lupus Erythematosus: A Case Report
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Ko Soon-Young
Lee Sang-Heon
Kim Hae-Rim
Seo Tae-Ho
Lee Seung-Min
Jang Yun-Mi
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Abstract
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Interstitial lung disease (ILD) with autoantibodies against antisynthetase may occur in the absence of clinically apparent myositis. We report 58-year-old woman who initially presented with dyspnea. The patient showed positive immunologic markers reflecting systemic lupus erythematosus, destructive polyarthritis, Raynaud’s phenomenon, and ILD. There is no proximal muscle weakness in her symptoms. This syndrome was confirmed by positive antibodies to Jo-1. For the early diagnosis of this syndrome, the possibility of this syndrome including other connective tissue disease should be considered in patients presenting with symptoms related to ILD and positive anti-nuclear antibody.
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KEYWORD
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Atnisynthetase syndrome, Anti-Jo-1 antibody, Interstitial lung diseases, Systemic lupus erythematosus
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